site stats

The global lipids genetics consortium glgc

WebThe gene expression signature for hyperlipidemia was estimated using the whole blood elastic net model (tissue = “TW_Whole_Blood_Elastic_Net_0.5”) [2] and GWAS summary statistics from the Global Lipids Genetics Consortium with 188,577 individuals (phenotype = “GLGC_Mc_LDL”). [3,4] The file was downloaded from “ … Web15 Jul 2024 · Using a global lipidomic analysis, another landmark study identified 12,13-dihydroxy-9Z-octadecenoic acid ... For the fasting lipid traits, we used the findings of the Global Lipids Genetics Consortium (GLGC; based on N of up to 94,595) . As outcome data, we used summary statistics of genome wide association study ...

Plasma lipids and risk of aortic valve stenosis: a Mendelian ...

Web5 Jun 2024 · We apply MTAR to rare-variant summary statistics for three lipid traits in the Global Lipids Genetics Consortium. 99 genome-wide significant genes were identified in … Web29 Mar 2024 · Shown are the multivariable MR (MVMR) results from the discovery analysis, using genetic instruments for plasma TG levels from Global Lipids Genetics Consortium (GLGC) and disease traits from UKB. Levels of statistical significance are categorized into three tiers: Tier 1 (BB): At least Bonferroni-significant in both the discovery (p<1.92 × 10 … huaraches negros https://5pointconstruction.com

GLGC - lipidgenetics.org

Web11 Sep 2024 · This study aimed to assess a potential causal relationship between genetic variants associated with plasma lipid traits (high-density lipoprotein, HDL; low-density lipoprotein, LDL; triglycerides, TGs) with risk for BC using Mendelian randomization (MR). Methods and findings Web27 Sep 2024 · Study overview. BCAC: Breast Cancer Association Consortium, Egger MR Egger method, EUR European reference sample, GLGC Global Lipids Genetics Consortium, HDL-C high-density lipoprotein-cholesterol ... hofmann leasing uslar

Discovery and refinement of loci associated with lipid levels

Category:- Queen Mary University of London

Tags:The global lipids genetics consortium glgc

The global lipids genetics consortium glgc

Frontiers Association of the gut microbiota with coronary artery ...

Web22 Apr 2024 · Variants were robustly associated with LDL-C in a meta-analysis of genome-wide association studies (GWAS) involving 188,578 individuals primarily (96%) of … Web28 Dec 2024 · Global Lipids Genetic Consortium (GLGC), acquire information predominantly from9 Europeans, and these within-European discoveries may not extrapolate to other10 populations [4–7].11 To...

The global lipids genetics consortium glgc

Did you know?

Web1 Apr 2024 · After a rigorous evaluation of the quality of studies, the single-nucleotide polymorphisms (SNPs) associated with the four blood lipids were selected from the Global Lipids Genetic... Web8 Aug 2024 · large lipid meta-analyses, such as the Global Lipids Genetics Consortium (GLGC), acquire information predominantly from Europeans, and these within-European …

WebDasman Diabetes Institute and Research Center is one of the best diabetes treatment centres in Kuwait. We provide the latest diabetes research and treatment in all over Kuwait. Our qualified doctors are working on the best diabetes treatment for patients. Web30 Mar 2024 · Total cholesterol and LDL cholesterol were corrected for lipid-lowering medication use, defined as any use of statins or any unspecified lipid-lowering medication …

http://csg.sph.umich.edu/willer/public/glgc-lipids2024/ WebGlobal Lipids Genetics Consortium Results Meta-Analysis Tables. The tables below summarize the results of the meta-analysis of exome chip in &gt; 300,000 primarily European …

Web9 Dec 2024 · The study was led by the Global Lipids Genetics Consortium (GLGC), an international collaboration of scientists investigating the genetic etiology of quantitative …

WebWe combine the GWAS results from the Global Lipids Genetics Consortium (GLGC) with functional genomics data from a number of tissue-specific eQTLs and the ENCODE project, and gene-gene relationship information from biological pathways and data-driven gene network studies. huaraches outfithttp://lipidgenetics.org/ hofmann lift partsWebThe Global Lipids Genetics Consortium aggregated GWAS results from 1,654,960 individuals from 201 primary studies representing five genetic ancestry groups: Admixed … hofmann leasing welshttp://csg.sph.umich.edu/willer/public/lipids2024/ huaraches on saleWeb26 Nov 2013 · Global Lipids Genetics Consortium Results Reference Willer CJ et al. Discovery and refinement of loci associated with lipid levels. Nat. Genet. 2013. … huarache spanishWeb2 Mar 2024 · The Global Lipids Genetics Consortium (GLGC) study is a genome-wide genotyping analysis of 188,577 individuals to search for loci associated with plasma lipid levels [21]. The aim of the FinnGen study is to research the national health registry data and genome of 500,000 Finns. huarache soldesWeb11 Mar 2024 · Genetic association estimates for LDL-c were obtained from a meta-analysis of genome-wide association studies (GWAS) conducted by the Global Lipids Genetics Consortium (GLGC). 19 The meta-analysis was restricted to participants of European ancestry, and most contributing cohorts measured blood lipid levels after 8 or more hours … huaraches oaxaca