WebbDr. Ramin Shiekhattar recently joined the University of Miami Miller School of Medicine as Professor in the Departments of Human Genetics and Biochemistry & Molecular Biology. … Webb9 mars 2007 · Min Gyu Lee 1 , Jessica Norman, Ali Shilatifard, Ramin Shiekhattar. Affiliation 1 The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA. PMID: 17320162 DOI: 10.1016/j.cell.2007.02.004 Abstract Histone methylation is a ...
Physical and functional association of a trimethyl H3K4 ... - PubMed
Webb1 juni 2024 · The authors thank the Shiekhattar laboratory members for discussions and helpful comments. RS is supported by the University of Miami Miller School of Medicine , … Webb2 okt. 2014 · In unicellular organisms, initiation is the rate-limiting step in transcription; in metazoan organisms, the transition from initiation to productive elongation is also important. Here, we show that the RNA polymerase II (RNAPII)-associated multiprotein complex, Integrator, plays a critical role in b … イオン 層
The Integrator complex at the crossroad of coding and noncoding …
Webb1 sep. 2024 · Activating mutations in the mitogen-activated protein kinase (MAPK) cascade, also known as the RAS-MEK-extracellular signal-related kinase (ERK1/2) pathway, are an underlying cause of >70% of human cancers. While great strides have been made toward elucidating the cytoplasmic components of MAPK signaling, the key downstream … Webb15 sep. 2005 · Min Gyu Lee 1 , Christopher Wynder, Neil Cooch, Ramin Shiekhattar. Affiliation 1 The Wistar Institute, 3601 Spruce Street, Philadelphia, Pennsylvania 19104, USA. PMID: 16079794 DOI: 10.1038/nature04021 Abstract We have previously ... WebbDr. Shiekhattar is the Director of Cancer Epigenetics Program, Chief of Division of Cancer Genomics & Epigenetics and Professor of Human Genetics at the University of Miami … otto autos