Cytohesin-2
WebMar 4, 1997 · Abstract. Cytohesin-1, a protein abundant in cells of the immune system, has been proposed to be a human homolog of the Saccharomyces cerevisiae Sec7 gene product, which is crucial in protein transport. More recently, the same protein has been reported to be a regulatory factor for the αLβ2 integrin in lymphocytes. WebPaxillin colocalizes with cytohesin-2 at the leading edges of migrating cells. This interaction is mediated by the LIM2 domain of paxillin and the isolated polybasic region of cytohe-sin-2. Importantly, migration is inhibited by expression of the constructs containing these regions. These results suggest that cytohesin-2, through a previously ...
Cytohesin-2
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WebJul 26, 2004 · Cytohesin-2 Is a Positive Effector of Gene Expression by Means of the SRE. The cytohesin class of small ARF-GEFs is implicated in the control of cytoskeleton … WebNov 1, 2024 · cytohesin-2 is a guanine nucleotide exchange factor to activate ARF1 and ARF6, which are involved in various biological processes, including signal transduction, cell differentiation, cell structure organization, and survival. Nevertheless, there is a lack of evidence revealing the role of cytohesin-2 in osteoclast differentiation and in the …
WebCytohesin-2 is enriched in the perisynapse on the postsynaptic membrane of dorsal horn neurons and forms a protein complex with mGluR5 in the spinal cord. Central nervous … Cytohesin-2 (CYTH2), formerly known as Pleckstrin homology, Sec7 and coiled/coil domains 2 (PSCD2), is a member of the cytohesin family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) … See more Cytohesin-2 is a protein that in humans is encoded by the CYTH2 gene. See more CYTH2 has been shown to interact with Arrestin beta 2 and Arrestin beta 1. See more • Meacci E, Tsai SC, Adamik R, Moss J, Vaughan M (1997). "Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor" See more
WebCytohesin-2 constitutively suppresses platelet dense granule secretion and aggregation by keeping ARF6 in a GTP-bound state. Expression of CYTH2 mutant deficient of the EFh2 domain in cells also inhibits Arf6 activation and neurite extension. The N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (V-ATPase) and ... WebCytohesin-1 and cytohesin-2 are ARF-1 guanine nucleotide exchange factors (GEFs). Biochemicals that inhibit cytohesin-2 have many applications in biochemical and physiological research. Click on the product name to view detailed information such as the chemical structure and specific chemical properties for each of our cytohesin-2 Inhibitors.
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WebJan 12, 2024 · The guanine nucleotide exchange factor cytohesin-2 (ARNO) is a major activator of the small GTPase ARF6 that has been shown to play an important role(s) in cell adhesion, migration and cytoskeleton reorganization in various cell types and models of disease. Interestingly, dysregulated cell migration, in tandem with hyper-inflammatory … iphone x used 64gbWebJul 30, 2010 · The cytohesin family is composed of cytohesin-1, cytohesin-2/ARNO, cytohesin-3/Grp1/ARNO3, and cytohesin-4 . To determine which of these cytohesins is … iphone x usb-cWebJan 12, 2024 · The guanine nucleotide exchange factor cytohesin-2 (ARNO) is a major activator of the small GTPase ARF6 that has been shown to play an important role(s) in … iphone x used cheapWebAug 5, 2024 · CYTH2 cytohesin 2 Gene ID: 9266, updated on 5-Aug-2024 Gene type: protein coding Also known as: ARNO; CTS18; PSCD2; SEC7L; PSCD2L; CTS18.1; Sec7p-L; Sec7p-like; cytohesin-2 See all available tests in GTR for this gene Go to complete Gene record for CYTH2 Go to Variation Viewer for CYTH2 variants Summary iphone x used attWebResults: Serum calumenin, S100A6, and cytohesin 2 were higher in Ssc patients compared to controls. Calumenin associated with extensive cutaneous fibrosis, frequency of … orange sushi anaheim caWebJun 21, 2024 · CYTH2 is a guanine nucleotide exchange factor (GEF) for the small GTP-binding protein ARF6 ( 600464 ), which is involved in cytoskeletal rearrangement ( Torii et al., 2014 ). Cloning and Expression iphone x usb hub clean laptopWeb胎牛血清（杂交瘤细胞专用） sp2/0 小鼠骨髓瘤细胞. 佐剂乳化器 orange sustainable living expo